Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Gdnf  glial cell line derived neurotrophic factor   (Synonyms: glial cell line-derived neurotrophic factor)
Results	Reference
1	J:174353 Boualia SK, Gaitan Y, Murawski I, Nadon R, Gupta IR, Bouchard M, Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for pax2 and emx2. PLoS One. 2011;6(6):e21529
1	J:90324 Grieshammer U, Le Ma, Plump AS, Wang F, Tessier-Lavigne M, Martin GR, SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site. Dev Cell. 2004 May;6(5):709-17
1*	J:34258 Hellmich HL, Kos L, Cho ES, Mahon KA, Zimmer A, Embryonic expression of glial cell-line derived neurotrophic factor (GDNF) suggests multiple developmental roles in neural differentiation and epithelial-mesenchymal interactions. Mech Dev. 1996 Jan;54(1):95-105
1*	J:172983 Kobayashi H, Kawakami K, Asashima M, Nishinakamura R, Six1 and Six4 are essential for Gdnf expression in the metanephric mesenchyme and ureteric bud formation, while Six1 deficiency alone causes mesonephric-tubule defects. Mech Dev. 2007 Apr;124(4):290-303
1*	J:60834 Kume T, Deng K, Hogan BL, Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract. Development. 2000 Apr;127(7):1387-95
1	J:86619 Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG, Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. Nature. 2003 Nov 20;426(6964):247-54
1	J:122519 Linton JM, Martin GR, Reichardt LF, The ECM protein nephronectin promotes kidney development via integrin {alpha}8{beta}1-mediated stimulation of Gdnf expression. Development. 2007 Jul;134(13):2501-9
1	J:157251 Lokmane L, Heliot C, Garcia-Villalba P, Fabre M, Cereghini S, vHNF1 functions in distinct regulatory circuits to control ureteric bud branching and early nephrogenesis. Development. 2010 Jan;137(2):347-57
1	J:156865 Michos O, Cebrian C, Hyink D, Grieshammer U, Williams L, D'Agati V, Licht JD, Martin GR, Costantini F, Kidney development in the absence of Gdnf and Spry1 requires Fgf10. PLoS Genet. 2010 Jan;6(1):e1000809
1*	J:40605 Miyamoto N, Yoshida M, Kuratani S, Matsuo I, Aizawa S, Defects of urogenital development in mice lacking Emx2. Development. 1997 May;124(9):1653-64
1*	J:171473 Nie X, Xu J, El-Hashash A, Xu PX, Six1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesis. Dev Biol. 2011 Apr 1;352(1):141-51
1	J:71242 Nishinakamura R, Matsumoto Y, Nakao K, Nakamura K, Sato A, Copeland NG, Gilbert DJ, Jenkins NA, Scully S, Lacey DL, Katsuki M, Asashima M, Yokota T, Murine homolog of SALL1 is essential for ureteric bud invasion in kidney development. Development. 2001 Aug;128(16):3105-15
1	J:221158 Okazawa M, Murashima A, Harada M, Nakagata N, Noguchi M, Morimoto M, Kimura T, Ornitz DM, Yamada G, Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development. Dev Biol. 2015 Apr 1;400(1):139-47
1	J:176574 Peng C, Aron L, Klein R, Li M, Wurst W, Prakash N, Le W, Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons. J Neurosci. 2011 Sep 7;31(36):12802-12815
1	J:107078 Poladia DP, Kish K, Kutay B, Hains D, Kegg H, Zhao H, Bates CM, Role of fibroblast growth factor receptors 1 and 2 in the metanephric mesenchyme. Dev Biol. 2006 Mar 15;291(2):325-39
1	J:166316 Saifudeen Z, Dipp S, Stefkova J, Yao X, Lookabaugh S, El-Dahr SS, p53 regulates metanephric development. J Am Soc Nephrol. 2009 Nov;20(11):2328-37
1*	J:100569 Sajithlal G, Zou D, Silvius D, Xu PX, Eya 1 acts as a critical regulator for specifying the metanephric mesenchyme. Dev Biol. 2005 Aug 15;284(2):323-36
1	J:115344 Self M, Lagutin OV, Bowling B, Hendrix J, Cai Y, Dressler GR, Oliver G, Six2 is required for suppression of nephrogenesis and progenitor renewal in the developing kidney. EMBO J. 2006 Nov 1;25(21):5214-28
1*	J:167305 Sims-Lucas S, Cusack B, Baust J, Eswarakumar VP, Masatoshi H, Takeuchi A, Bates CM, Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development. Dev Dyn. 2011 Jan;240(1):240-9
1	J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30
1*	J:88686 Wellik DM, Hawkes PJ, Capecchi MR, Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev. 2002 Jun 1;16(11):1423-32
1*	J:37282 Wright DE, Snider WD, Focal expression of glial cell line-derived neurotrophic factor in developing mouse limb bud. Cell Tissue Res. 1996 Nov;286(2):209-17
1*	J:83432 Xu PX, Zheng W, Huang L, Maire P, Laclef C, Silvius D, Six1 is required for the early organogenesis of mammalian kidney. Development. 2003 Jul;130(14):3085-94